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Item EH017002: Two alleles of the same gene have some nucleotides in common in their DNA sequences and some that are different.

Which of the following correctly describes the relationship between two different alleles of the same gene and the DNA sequences of those alleles?

  1. Two alleles of the same gene are completely different. Their DNA sequences do not have any nucleotides in common.
  2. Two alleles of the same gene have some nucleotides in common in their DNA sequences and some that are different.
  3. Two alleles of the same gene are identical. All of their nucleotides are the same and they are in the same order.
  4. There is no relationship between nucleotides and alleles. Nucleotides make up a gene, not an allele.

Pre-Test

Distribution of responses (prior to studying evolution in high school)
Answer Choice
Overall
Grades
Gender
Primary Language
 
n = 572
6–8
n = 18
9–12
n = 502
Male
n = 245
Female
n = 283
English
n = 511
Other
n = 18
A. Two alleles of the same gene are completely different. Their DNA sequences do not have any nucleotides in common. 13% 22% 12% 13% 13% 13% 6%
B. Two alleles of the same gene have some nucleotides in common in their DNA sequences and some that are different. 52% 50% 53% 52% 53% 52% 44%
C. Two alleles of the same gene are identical. All of their nucleotides are the same and they are in the same order. 23% 11% 24% 25% 22% 23% 28%
D. There is no relationship between nucleotides and alleles. Nucleotides make up a gene, not an allele. 12% 17% 12% 10% 12% 12% 22%

Post-Test (Control)

Distribution of responses (following typical high school instruction on evolution)
Answer Choice
Overall
Grades
Gender
Primary Language
 
n = 274
6–8
n = 14
9–12
n = 230
Male
n = 119
Female
n = 130
English
n = 237
Other
n = 9
A. Two alleles of the same gene are completely different. Their DNA sequences do not have any nucleotides in common. 12% 36% 11% 12% 13% 12% 33%
B. Two alleles of the same gene have some nucleotides in common in their DNA sequences and some that are different. 55% 50% 55% 53% 57% 55% 44%
C. Two alleles of the same gene are identical. All of their nucleotides are the same and they are in the same order. 22% 14% 23% 25% 21% 23% 22%
D. There is no relationship between nucleotides and alleles. Nucleotides make up a gene, not an allele. 11% 0% 10% 10% 9% 10% 0%

Post-Test (Treatment)

Distribution of responses (following completion of an evolution curriculum module)
Answer Choice
Overall
Grades
Gender
Primary Language
 
n = 278
6–8
n = 4
9–12
n = 248
Male
n = 130
Female
n = 131
English
n = 251
Other
n = 5
A. Two alleles of the same gene are completely different. Their DNA sequences do not have any nucleotides in common. 10% 25% 9% 12% 8% 9% 40%
B. Two alleles of the same gene have some nucleotides in common in their DNA sequences and some that are different. 69% 25% 71% 66% 71% 70% 60%
C. Two alleles of the same gene are identical. All of their nucleotides are the same and they are in the same order. 14% 50% 14% 16% 13% 15% 0%
D. There is no relationship between nucleotides and alleles. Nucleotides make up a gene, not an allele. 6% 0% 6% 6% 8% 6% 0%