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Item CA031003: Organisms can decode the information in each other's genes to build similar structures (wrists and fingers in mice; bones in the fins of fish).

The evolution of hands and arms from fins is one of the most important changes to occur in the history of vertebrates. There are only two groups of bones in the fins of living fish (long bones and short bones), but there are three groups of bones in the limbs of other vertebrates such as mice (arms, wrists, and fingers).

Short and long bones in the fins of fish                      Arms, wrists, and fingers in mice

Which of the following would provide evidence that both wrists and fingers of mice evolved from the SHORT bones of the fins of fish?

  1. If the DNA needed for wrist and finger growth in mice also exists in fish DNA.
  2. If during mouse development, both wrist and finger bones grew from a set of bones similar to the LONG bones in fish fins.
  3. If DNA that is needed for the development of the LONG bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice not developing normal wrists and fingers.
  4. If DNA that is needed for the development of SHORT bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice developing normal wrists and fingers.

The scenario presented here is based on an actual scientific study (Gehrke, et. al.  2015); however, it has been simplified for testing purposes.

Pre-Test

Distribution of responses (prior to studying evolution in high school)
Answer Choice
Overall
Grades
Gender
Primary Language
 
n = 559
6–8
n = 23
9–12
n = 499
Male
n = 221
Female
n = 300
English
n = 516
Other
n = 13
A. If the DNA needed for wrist and finger growth in mice also exists in fish DNA. 27% 9% 27% 26% 26% 26% 31%
B. If during mouse development, both wrist and finger bones grew from a set of bones similar to the LONG bones in fish fins. 26% 39% 26% 26% 25% 26% 23%
C. If DNA that is needed for the development of the LONG bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice not developing normal wrists and fingers. 20% 22% 20% 22% 19% 20% 15%
D. If DNA that is needed for the development of SHORT bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice developing normal wrists and fingers. 28% 30% 27% 26% 30% 27% 31%

Post-Test (Control)

Distribution of responses (following typical high school instruction on evolution)
Answer Choice
Overall
Grades
Gender
Primary Language
 
n = 281
6–8
n = 18
9–12
n = 229
Male
n = 109
Female
n = 135
English
n = 243
Other
n = 9
A. If the DNA needed for wrist and finger growth in mice also exists in fish DNA. 31% 17% 31% 38% 24% 30% 33%
B. If during mouse development, both wrist and finger bones grew from a set of bones similar to the LONG bones in fish fins. 28% 56% 28% 23% 36% 29% 44%
C. If DNA that is needed for the development of the LONG bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice not developing normal wrists and fingers. 19% 0% 19% 17% 18% 18% 0%
D. If DNA that is needed for the development of SHORT bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice developing normal wrists and fingers. 22% 28% 22% 22% 21% 22% 22%

Post-Test (Treatment)

Distribution of responses (following completion of an evolution curriculum module)
Answer Choice
Overall
Grades
Gender
Primary Language
 
n = 305
6–8
n = 3
9–12
n = 280
Male
n = 139
Female
n = 150
English
n = 276
Other
n = 8
A. If the DNA needed for wrist and finger growth in mice also exists in fish DNA. 23% 0% 24% 19% 27% 24% 25%
B. If during mouse development, both wrist and finger bones grew from a set of bones similar to the LONG bones in fish fins. 31% 67% 30% 38% 24% 31% 38%
C. If DNA that is needed for the development of the LONG bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice not developing normal wrists and fingers. 15% 0% 15% 13% 15% 14% 25%
D. If DNA that is needed for the development of SHORT bones in fish is inserted into mice that haven't been able to grow wrists and fingers results in the mice developing normal wrists and fingers. 31% 33% 31% 29% 33% 32% 13%